SCHEDULE


Friday, May 3

Registration


8:00 AM - 1:00 PM
Venue: Marvin Center, Lobby

Opening and Welcome Remarks


1:00 PM - 1:10 PM
Venue: Marvin Center, Amphitheater

Keynote


Christina Leslie


1:10 PM - 2:10 PM


Venue: Marvin Center, Amphitheater

Cancer Evolution


Chair: Layla Oesper

Distance Measures for Tumor Evolutionary Trees


Speaker: Zach DiNardo and Kiran Tomlinson
2:10 PM - 2:30 PM
Venue: Marvin Center, Amphitheater

Summarizing the Solution Space in Tumor Phylogeny Inference by Multiple Consensus Trees [Late Breaking Research]


Speaker: Mohammed El-Kebir
2:30 PM - 2:50 PM
Venue: Marvin Center, Amphitheater

Minimal functional driver gene heterogeneity among untreated metastases [Highlight]


Speaker: Johannes G. Reiter
2:50 PM - 3:10 PM
Venue: Marvin Center, Amphitheater

Identifying Drug Sensitivity Subnetworks with NETPHLIX [Late Breaking Research]


Speaker: Yoo-Ah Kim
3:10 PM - 3:30 PM
Venue: Marvin Center, Amphitheater

Coffee Break


3:30 PM - 4:00 PM
Venue: Marvin Center, Room 309

Transcriptomics I


Chair: Yoo-Ah Kim

Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers [Late Breaking Research]


Speaker: Hatice Osmanbeyoglu
4:00 PM - 4:20 PM
Venue: Marvin Center, Amphitheater

Deep Genomic Signature for early metastasis prediction in prostate cancer


Speaker: Oliver Snow
4:20 PM - 4:40 PM
Venue: Marvin Center, Amphitheater

Poster Session


5:00 PM - 6:00 PM


Venue: Marvin Center, Room 309

Saturday, May 4

Keynote


Joel Saltz


8:50 AM - 9:50 AM


Venue: Marvin Center, Amphitheater

Transcriptomics II


Chair: Yoo-Ah Kim

Integrated Transcriptomic-Genomic tool Texomer profiles cancer tissues [Highlight]


Speaker: Ken Chen
9:50 AM - 10:10 AM
Venue: Marvin Center, Amphitheater

Uncovering and characterizing splice variants associated with survival in lung cancer patients


Speaker: Sean West
10:10 AM - 10:30 AM
Venue: Marvin Center, Amphitheater

Coffee Break


10:30 AM - 11:00 AM
Venue: Marvin Center, Room 309

Pathways


Chair: Ben Raphael

Uncovering the subtype-specific temporal order of cancer pathway dysregulation


Speaker: Oliver Snow
11:00 AM - 11:20 AM
Venue: Marvin Center, Amphitheater

An Estrogen Regulated Feedback Loop Limits the Efficacy of Estrogen Receptor Targeted Breast Cancer Therapy [Highlight]


Speaker: Wei Li
11:20 AM - 11:40 AM
Venue:Marvin Center, Amphitheater

Modeling Clinical and Molecular Covariates of Mutational Process Activity in Cancer [Late Breaking Research]


Speaker: Welles Robinson
11:40 AM - 12:00 PM
Venue: Marvin Center, Amphitheater

Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures [Highlight]


Speaker: Joo Sang Lee
12:00 PM - 12:20 PM
Venue: Marvin Center, Amphitheater

Lunch Break


12:20 PM - 1:50 PM

Keynote


Eytan Ruppin


1:50 PM - 2:50 PM


Venue: Marvin Center, Amphitheater

Proteomics


Chair: Max Leiserson

Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling [Highlight]


Speaker: Emmanuel Barillot
2:50 PM - 3:10 PM
Venue: Marvin Center, Amphitheater

High-throughput binding prediction of Class I and Class II neoantigens with MHCnuggets [Late Breaking Research]


Speaker: Xiaoshan Melody Shao
3:10 PM - 3:30 PM
Venue: Marvin Center, Amphitheater

Coffee Break


3:30 PM - 4:00 PM
Venue: Marvin Center, Room 309

Single Cell


Chairs: Rachel Karchin

SCMarker: ab initio marker selection for single cell transcriptome profiling


Speaker: Ken Chen
4:00 PM - 4:20 PM
Venue: Marvin Center, Amphitheater

Inference of single-cell genotypes characterizes the genetic heterogeneity in pancreatic cancer precursor lesions [Highlight]


Speaker: Violeta Beleva Guthrie
4:20 PM - 4:40 PM
Venue: Marvin Center, Amphitheater

Single-cell phylogenetic inference with copy-number supported mutation losses [Late Breaking Research]


Speaker: Gryte Satas
4:40 PM - 5:00 PM
Venue: Marvin Center, Amphitheater

SCIFIL: analysis of evolutionary history and clonal selection in cancer populations using single-cell sequencing data


Speaker: Pavel Skums
5:00 PM - 5:20 PM
Venue: Marvin Center, Amphitheater

Closing Remarks


5:20 PM - 5:35 PM
Venue: Marvin Center, Amphitheater

Reception


6:00 PM - 8:00 PM


Venue: Marvin Center, Room 309